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吸入纳米颗粒系统:组成,制造和气溶输送

Heidi M Mansour^1,2,3,4, Priya Muralidharan¹, Don Hayes^5,6

¹College of Pharmacy, Skaggs Pharmaceutical Sciences Center, The University of Arizona, Tucson, Arizona, USA.

Journal of aerosol medicine and pulmonary drug delivery

|August 22, 2024

概括

纳米技术为COPD和喘等疾病提供有针对性的肺药物输送. 液体或固体形式的纳米粒子可以被设计为精确的肺部治疗和改善治疗结果.

科学领域:

肺部医学肺部医学
纳米技术纳米技术
药物输送系统药物输送系统

背景情况:

纳米技术在医学中的作用正在扩大,随着产品批准的增加.
针对性治疗对于有效治疗各种肺部疾病至关重要.

研究的目的:

探索纳米技术在向性肺部药物输送中的应用.
对肺部疾病的各种纳米载体类型和吸入气溶技术进行审查.

主要方法:

讨论纳米粒子属性 (大小,表面变化) 用于特定地点的准.
纳米载体的分类 (液体,固体) 和它们的药物载体能力 (水友性,疏水性).
聚合物纳米载体架构和配方策略的概述.

主要成果:

纳米粒子可以被设计为有针对性的传送到特定的肺部区域.
各种纳米载体类型和气溶平台可用于肺部药物输送.
固态纳米粒子配方提供了增强的稳定性和多功能性.

结论:

纳米技术为治疗COPD,喘和感染等肺部疾病提供了创新的解决方案.
定制纳米载体特性和配方是有效的肺部药物输送的关键.
本综述涵盖纳米载体,气溶装置和用于吸入治疗的粒子工程.

关键词:

气溶的准目标生物材料是一种生物材料.合物分散的合物分散.控制的药物释放控制的药物释放吸入粉末的吸入粉末粘液的透粘液的透纳米技术是纳米技术.粒子工程设计的设计聚合物是一种聚合物.

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