系统性自身炎症性疾病,IgA球体炎和皮层亡:巧合还是因果关系?
Carlos Chiurchiu1,2, Pehuén Fernández1,2, Walter Douthat1,2
1Servicio de Nefrología, Hospital Privado Universitario de Córdoba, Córdoba, Argentina.
Medicina
|August 22, 2024
概括
一个罕见的自身炎症性疾病 - - 梅瓦诺酸激酶缺乏症 (Mevalonate kinase deficiency,MKD) 与一名患者的IgA脏病和皮层缩有关. 卡纳基努马布在治疗MKD症状和相关脏问题的治疗方面表现有前途.
科学领域:
- 遗传学和免疫学 遗传学和免疫学
- 罕见的自身炎症性疾病是罕见的.
- 腎臟病學 (nephrology) 是一種醫學專業.
背景情况:
- 梅瓦诺酸激酶缺乏症 (MKD) 是一种罕见的自身炎症性疾病.
- IgA脏病是一种常见的淋巴结核炎形式.
- 系统性炎症和病之间的相互作用是复杂的.
相关概念视频
Autoimmune Disorders
398
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
Concept and Mechanism of Autoimmune Diseases
The immune...
398
Gastritis-II: Pathophysiology
287
Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
287
Renal Corpuscle
1.8K
The glomerulus and Bowman's capsule are two essential components of the nephron, which is the functional unit of the kidney. These microscopic structures play a critical role in the process of blood filtration to produce urine.
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous...
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous...
1.8K
Inflammatory Bowel Disease II: Crohn's Disease
205
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
205


