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Updated: Jun 20, 2026

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聚化/mRNA纳米粒子的超分子组合和体内单细胞编程

Yizong Hu1,2,3, Stephany Y Tzeng2,3, Leonardo Cheng1,2,3

  • 1Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD 21218.

Proceedings of the National Academy of Sciences of the United States of America
|August 22, 2024
PubMed
概括

研究人员开发了更大的纳米颗粒,用于向向单细胞的基因传递. 这些400纳米粒子有效地传递信使RNA (mRNA),将单细胞编程成巨细胞并增强抗癌免疫力.

关键词:
提供mRNA的交付.一个单细胞的转化转化.纳米粒子组装组件的组件聚乙酸氨基) 是一种聚乙酸氨基.车辆大小介导的被动定位.

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Ribosome synthesis is a highly complex and coordinated process involving more than 200 assembly factors. The synthesis and processing of ribosomal components occurs not only in the nucleolus but also in the nucleoplasm and the cytoplasm of eukaryotic cells.
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