检查心血管疾病患者住院期间认知功能变化的比例和特征
Takahiro Shimoda1, Shinzi Suzuki2, Daisuke Mizukoshi2
1Department of Preventive Gerontology, Center for Gerontology and Social Science, National Center for Geriatrics and Gerontology, Aichi, Japan.
PloS one
|August 22, 2024
概括
住院的心血管疾病患者在近一半的病例中表现出认知能力的改善,约20%的病例出现下降. 评估这些患者的认知变化对于更好的结果至关重要.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 老年病的医生 老年病的医生
背景情况:
- 心血管疾病 (CVD) 显著影响认知功能.
- 了解心血管疾病患者住院期间的认知变化是必不可少的,但尚未得到充分证实.
- 对心血管疾病患者认知能力下降的相关风险因素需要进一步调查.
研究的目的:
- 确定住院心血管疾病患者认知功能变化的比例和特征.
- 在住院期间识别与认知能力改善或下降相关的因素.
主要方法:
- 认知功能在入院和出院时使用迷你精神状态检查 (MMSE) 和蒙特利尔认知评估 (MoCA-J) 的日本版本进行了评估.
- 患者被分为认知障碍,轻度认知障碍 (MCI) 和非认知障碍组.
- 在MMSE或MoCA-J得分中≥2分的变化定义了改善或下降;其他被归类为维持.
主要成果:
- 在542名患者中,41.3%的人患有认知障碍,40.2%的人患有MCI,18.5%的人在入院时没有认知障碍.
- 在出院时,46.6%的人表现出认知能力的改善,35.9%的人保持了认知功能,17.5%的人经历了认知能力的下降.
- 多变量分析表明,入院和年轻时的MCI或认知障碍与认知改善有关;没有任何因素与认知衰退有显著的关联.
结论:
- 近一半住院的心血管疾病患者的认知能力有所改善,约20%的认知能力有所下降.
- 对心血管疾病患者住院期间进行认知功能评估至关重要.
- 需要进一步的研究来确定影响这一群体认知变化的特定因素.
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