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相关概念视频

Long-term Depression01:05

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Depression: Overview01:18

Depression: Overview

Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...

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Path analysis of factors associated with nurses' pain management practices in older adults with cognitive impairment: A cross-sectional study.

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相关实验视频

Updated: May 10, 2026

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats
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脑卒中后抑郁症与功能结果之间的关联:系统性审查.

Nipaporn Butsing1, Jaclene A Zauszniewski2, Suebsarn Ruksakulpiwat3

  • 1Ramathibodi School of Nursing, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

PloS one
|August 22, 2024
PubMed
概括

脑卒中后抑郁症 (PSD) 是常见的,并且与中风后功能恢复不良有关. 早期评估和PSD的管理对于改善患者的治疗结果至关重要.

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科学领域:

  • 神经学 神经学
  • 精神病学是一个精神病学.
  • 康复医学 康复医学 康复医学

背景情况:

  • 脑卒中后抑郁症 (PSD) 是一种影响中风患者康复的重大并发症.
  • 目前关于PSD与功能结果之间的联系的研究仍然不一致.

研究的目的:

  • 系统地审查PSD的流行情况.
  • 调查中风幸存者的PSD和功能结果之间的关联.

主要方法:

  • 非实验性研究的系统审查 (队列,横截面,病例控制).
  • 在PubMed,MEDLINE,Web of Science,CINAHL Plus中搜索到2024年1月.
  • 使用PRISMA指南选文献,并使用Joanna Briggs研究所的标准进行评估.

主要成果:

  • 后视障碍的患病率有所不同:12.2%-32.2% (2周),17.9%-35.5% (1个月),10.4%-32.0% (3个月).
  • 在中风1个月至5年后,发现PSD和功能性结果 (依赖,ADL,IADL,身体/认知功能) 之间存在显著的负面关联.
  • 抑郁症治疗对功能结果产生了积极的影响.

结论:

  • 在中风后的最初三个月观察到高PSD患病率.
  • PSD与功能性结果的下降密切相关.
  • 定期PSD评估和管理对于最佳中风恢复至关重要.