在9/11事件后的退伍军人中,关于酒精使用和认知困难的观察性队列研究,有或没有TBI和PTSD
April C May1, Rebecca C Hendrickson2, Kathleen F Pagulayan3
1Sierra Pacific Mental Illness Research and Education Clinical Center (MIRECC), Palo Alto Veterans Affairs Health Care System, Palo Alto, CA 94304, USA; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA.
Drug and alcohol dependence
|August 22, 2024
概括
较高的酒精消费,即使在下降,也会增加TBI或PTSD的退伍军人认知诊断风险. 长期的酒精使用模式对于识别有风险的个体至关重要.
科学领域:
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
- 军事医学 军事医学
背景情况:
- 创伤性脑损伤 (TBI),创伤后应激障碍 (PTSD) 和酒精使用在退伍军人中很常见.
- 这些情况独立地增加了认知困难.
- 脑损伤,创伤后应激障碍和酒精对认知诊断的综合影响不太清楚.
研究的目的:
- 研究退伍军人TBI和/或PTSD的酒精使用模式和认知诊断之间的关联.
- 确定与认知衰退相关的特定酒精消费轨迹.
主要方法:
- 利用了193,663名退伍军人的电子健康记录.
- 将退伍军人分类为饮酒轨迹组:使用AUDIT-C评分,始终低,最初高至低,最初中等至高.
- 采用Cox的比例危险模型来评估风险,调整人口统计和并发症.
主要成果:
- 退伍军人最初高至低 (HR=1.21) 和中等至高 (HR=1.42) 的酒精使用,与持续低饮酒者相比,认知诊断的风险明显更大.
- 创伤性脑损伤 (HR=5.40) 和创伤后应激障碍 (HR=2.42) 独立地与提高认知诊断风险有关.
- 酒精使用模式,TBI和PTSD共同影响认知健康结果.
结论:
- 增加的酒精消费,即使在下降,也与TBI/PTSD退伍军人的认知诊断风险增加有关.
- 长期饮酒模式是认知障碍临床评估的关键因素.
- 干预措施应考虑酒精使用轨迹,以识别和支持处于危险的退伍军人.
相关概念视频
Post-traumatic Stress Disorder
30
Post-traumatic stress disorder (PTSD) is a psychiatric condition that arises following exposure to traumatic events such as natural disasters, forced displacement, or severe accidents. It significantly impairs individuals' ability to cope with daily activities and disrupts their emotional and psychological equilibrium.
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events,...
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events,...
30
Observational Studies
8.4K
Observational studies are a type of analytical study where researchers observe events without any interventions. In other words, the researcher does not influence the response variable or the experiment's outcome.
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
8.4K
Cognitive Development During Adulthood
72
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
72
Substance Use Disorders Affecting Sleep
163
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Understanding the concepts of physical dependence,...
163


