JOSA:联合基于表面的注册和大脑几何和功能图谱的构建
Jian Li1, Greta Tuckute2, Evelina Fedorenko3
1A. A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, United States of America; Center for Neurotechnology and Neurorecovery, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, United States of America.
乔萨是大脑注册的新框架,它对大脑结构和功能进行了对齐. 它通过模拟不匹配来提高准确性,即使在使用过程中没有功能数据.
科学领域:
- 神经成像是一种神经成像.
- 医学图像分析 医学图像分析
- 计算神经科学是一种神经科学.
背景情况:
- 基于表面的皮质注册对于医学图像分析至关重要.
- 目前的方法依赖于几何特征,假设折叠模式与大脑功能保持一致,但通常情况并非如此.
研究的目的:
- 引入JOSA,一个用于皮层注册的新框架.
- 共同建模几何和功能不匹配,以改善注册.
- 开发一个公正的,特定于人口的地图.
主要方法:
- 乔萨采用半监督的培训策略.
- 它共同模拟了大脑几何和功能之间的不匹配.
- 该框架同时学习特定人口的地图.
主要成果:
- 与最先进的方法相比,JOSA在几何和功能上都表现出优越的注册性能.
- 该框架实现了高精度,在推断过程中不需要功能数据.
- 它可以扩展,包括各种辅助数据类型用于注册指导.
结论:
- 乔萨 (JOSA) 通过承认几何-功能不匹配,为皮层注册提供了一种新的方法.
- 该框架为分析大脑结构和功能提供了强大的工具.
- 它为未来的注册方法打开了道路,整合了多式模式的大脑数据.
更多相关视频
09:06Whole-brain Segmentation and Change-point Analysis of Anatomical Brain MRI—Application in Premanifest Huntington's Disease
Published on: June 9, 2018
05:23Author Spotlight: Noninvasive Cerebral Blood Flow Determination in Human Functional Brain Region for Diagnosis of Neurological Disorders
Published on: May 31, 2024
相关概念视频
Neuron Structure
Neuron Structure
Structure and Function of Neurons
The neuronal cell body—the soma— houses the nucleus and organelles vital to cellular...
Structural Organization of the Human Body: An Overview
To study the chemical level of organization, scientists consider the simplest building blocks of matter: subatomic particles, atoms, and molecules. All matter in the universe is composed of one or more unique pure substances called elements, familiar examples of...
Anatomy of the Brain: Major Regions
The cerebrum is the largest section of the brain and divides into left and right hemispheres, separated by a deep fissure. The cerebral outer layer of grey matter — the cerebral cortex — comprises elevations called gyri and shallow groves called sulci. The inner portion of white matter includes long nerve fibers known as axons, which connect various areas...
Functional Brain Systems: Reticular Formation
Within the reticular formation, there are several distinct nuclei that can be classified into three broad categories. The Raphe nuclei are located along the midline of the brainstem. They are primarily known for their role in synthesizing and releasing serotonin, a neurotransmitter involved in regulating mood, appetite, sleep, and circadian rhythms. The...
Organization of the Brain
Hindbrain
The hindbrain, located at the base of the brain, plays a vital role in regulating automatic processes that sustain life. It includes the medulla oblongata, which is essential for...
