一项随机临床试验,以评估ADHD青少年新型执行工作记忆训练的可行性,耐受性和初步目标参与度
Abigail J Sullivan1, Jacey Anderson1, Morgan Beatty1
1Olin Neuropsychiatry Research Center, Hartford HealthCare, Hartford, CT, 06106, USA.
Behaviour research and therapy
|August 22, 2024
概括
这项研究表明,执行工作记忆 (EWM) 训练,专注于灵活性和稳定性,改善了青少年的ADHD症状. 该EWM培训是可行的,耐受性很好,并显示出有前途的行为改善.
科学领域:
- 神经科学是一个神经科学.
- 心理学 心理学 心理学
- 临床研究 临床研究
背景情况:
- 对注意力缺陷/多动障碍 (ADHD) 的工作记忆能力培训产生了不一致的结果.
- 执行工作记忆 (EWM) 过程,包括灵活性和稳定性,为ADHD提供了替代的训练目标.
研究的目的:
- 评估一个新的ADHD的EWM培训计划的可行性,耐受性和行为目标参与度.
- 研究EWM过程作为ADHD的潜在治疗点.
主要方法:
- 一项随机的,安慰剂控制的研究,涉及62名患有多动症的青少年 (12-18岁).
- 参与者在4-5周内接受了20次远程辅导的EWM培训或安慰剂课程.
- 主要结果包括对EWM任务的行为变化;次要结果评估了耐受性,保留和适应性难度参与.
主要成果:
- 干预参与者在EWM任务准确性 (转移,过) 和反应时间 (转移,更新) 中表现出中等效果大小的改善.
- 参与者报告了高的动机,情绪和参与度,并通过适应性训练难度成功地取得了进展.
- 观察到高的试验保留率,表明良好的耐受性和参与度.
结论:
- 执行工作记忆过程显示出作为ADHD有效训练目标的前景.
- 这些发现支持了EWM培训在改善ADHD行为结果方面的潜力.
- 计划进行扩展性临床试验,以复制并进一步调查这些有希望的结果.
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