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Updated: Jun 15, 2025

Mass Spectrometry and Luminogenic-based Approaches to Characterize Phase I Metabolic Competency of In Vitro Cell Cultures
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在人类肝脏显微体中,多尼佩西尔和塔达拉菲尔之间的P450细胞染色体介导的代谢相互作用

Jieun Yu1, Ji Hyeon Ryu1, Yong Ha Chi2

  • 1College of Pharmacy, Chungnam National University, Daejeon, Republic of Korea.

Toxicology in vitro : an international journal published in association with BIBRA
|August 22, 2024
PubMed
概括

塔达拉菲尔 (用于勃起功能障碍) 可以通过抑制CYP3A4.4来增加多尼佩西尔 (用于痴呆症) 水平. 这种药物相互作用主要是由于tadalafil.

关键词:
细胞染色体的抑制作用.在巴西完成了.药物相互作用 药物相互作用在体外代谢的代谢.塔达拉菲尔 (tadalafil) 是一个药物.

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