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孕期和哺乳期益生菌补充剂对婴儿过敏疾病的影响:一项随机对照试验
Debra J Palmer1, Alana R Cuthbert2, Thomas R Sullivan3
1Telethon Kids Institute, The University of Western Australia, Nedlands, Australia; School of Medicine, The University of Western Australia, Crawley, Australia.
The Journal of allergy and clinical immunology
|August 22, 2024
概括
在一项随机试验中,孕妇在怀孕和哺乳期间服用益生菌补充剂并没有显著降低婴儿湿疹风险. 这种饮食策略在预防高危婴儿过敏疾病方面没有任何好处.
科学领域:
- 免疫学 免疫学 免疫学
- 营养科学 营养科学
- 儿科 儿科 儿科
背景情况:
- 孕妇在怀孕和哺乳期间服用益生菌可能会调节婴儿的免疫系统.
- 这可能会降低婴儿过敏疾病的发病率.
研究的目的:
- 调查母体的益生菌补充剂是否可以降低遗传性倾向的婴儿的过敏结果.
- 这项研究旨在评估对医学诊断的婴儿湿疹,过敏原敏感性,食物过敏和反复喘息的影响.
主要方法:
- 一项双盲随机受控试验涉及孕妇从怀孕早期到产后6个月服用益生菌 (银和果-寡糖) 或安慰剂.
- 婴儿被监测过敏结果,主要是医学诊断的湿疹1岁.
主要成果:
- 在益生菌和安慰剂组 (31.5%与32.6%) 之间,在1岁时医学诊断的婴儿湿疹发生率没有显著差异.
- 二次过敏结果和安全措施也显示,两组之间没有显著差异.
结论:
- 在怀孕和哺乳期间,母亲的益生菌补充剂提供了很少的证据,以减少医学诊断的婴儿湿疹1岁.
- 研究结果表明,这种饮食干预可能无法有效预防遗传风险的婴儿过敏疾病.
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