在头部和部区域进行放射治疗后预防癌症 - - 一个系统性审查
Benedikt Luka1, Annelie Fiedler2, Carolina Ganss3
1Hannover Medical School, Department of Conservative Dentistry, Periodontology and Preventive Dentistry, Carl-Neuberg-Straße 1, 30625 Hannover, Germany.
The journal of evidence-based dental practice
|August 22, 2024
概括
强化化物应用对于在接受放射治疗的头癌患者中预防肆虐的牙至关重要. 严格使用可显著减少虫的增加,突出其在口腔健康管理中不可或缺的作用.
科学领域:
- 在瘤学瘤学.
- 牙科 牙科是指牙科的专业.
- 放射学 放射学是指放射学
背景情况:
- 对头部和部区域 (HN) 的放射治疗显著增加了严重脏病发展的风险.
- 对接受HN放射治疗的患者来说,强化脏预防策略是必不可少的.
- 这一系统审查评估了各种预防措施的有效性.
研究的目的:
- 系统地审查和总结有关头部和部放射治疗的患者虫预防措施有效性的证据.
- 确定最有效的干预措施来缓解辐射诱导的.
主要方法:
- 对临床研究进行系统审查,比较HN放射治疗患者的空预防干预与对照.
- 在主要数据库 (PubMed,科学网,谷歌学者,科克兰图书馆) 进行的搜索,截至2024年1月.
- 使用RoB2评估的偏差风险;数据因异质性而进行了定性总结,排除了元分析.
主要成果:
- 包括5项与355名参与者的研究,涉及诸如化物凝,重矿化溶液和饮食改变等干预措施.
- 虫得分每年从0.48增加到9.2的腐烂,缺失或填充表面 (DMF-S).
- 在不充分和严格的化物应用的组之间观察到病增加的显著差异.
结论:
- 在HN放射治疗后预防空的现有临床研究是有限的,并且具有方法上的弱点.
- 尽管存在局限性,但有强有力的证据支持化物在预防这些患者下的不可或缺作用.
- 严格的化物应用在减少病进展方面显示出很大的效果大小.
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