代际和遗传影响身体活动:来自HUNT研究的家庭数据,挪威,挪威
Mats Flaaten1, Eivind Schjelderup Skarpsno2, Atle Kongsvold2
1Department of Public Health and Nursing, Norwegian University of Science and Technology, Trondheim, Norway mats.flaaten@ntnu.no.
British journal of sports medicine
|August 22, 2024
概括
父母的身体活动和后代的遗传倾向都会影响成年人的身体活动水平. 然而,这些因素并没有协同作用,这表明以家庭为基础的促进运动的方法可能是有效的.
科学领域:
- 行为遗传学行为遗传学
- 公共卫生 公共卫生
- 运动科学运动科学
背景情况:
- 父母的生活方式选择显著影响后代的健康行为.
- 通过多基因风险评分量化的遗传倾向在个体体育活动水平上起作用.
研究的目的:
- 为了研究父母的身体活动和成年后代的身体活动之间的联系.
- 为了确定后代对身体活动的遗传责任是否会改变这种关联.
主要方法:
- 利用了来自Trøndelag健康研究的数据,这是一个基于人口的纵向队列.
- 基于父母活动水平 (设备测量和自我报告) 和后代的多基因风险评分,计算了身体活动的几率比率.
主要成果:
- 身体活跃的父母的后代在满足体育活动建议的几率更高 (ORs从1.78到1.93不等).
- 较高的多基因风险得分与后代的体力活动增加有关.
- 在父母活动和后代的遗传风险之间没有发现显著的乘法协同效应.
结论:
- 父母的影响和遗传倾向都与成年后代的身体活动独立相关.
- 父母的体力活动和后代的遗传风险得分之间的效果修改并不明显.
- 一个以家庭为中心的促进体育活动的策略对公共健康有很大的承诺.
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