Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Metastasis02:30

Metastasis

5.5K
Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
5.5K
Tumor Immunotherapy01:27

Tumor Immunotherapy

493
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
493
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

7.5K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
7.5K
The Tumor Microenvironment02:17

The Tumor Microenvironment

6.6K
Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
6.6K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Preterm infant formulas with glucose polymers and reduced lactose content increase the risk of necrotizing enterocolitis.

Frontiers in nutrition·2026
Same author

Potential Benefit of Sodium-Glucose Cotransporter 2-Inhibitors in Cisplatin-Associated Nephrotoxicity Among Patients With Cancer Having Diabetes Mellitus.

Kidney international reports·2026
Same author

Characterization of Genetic Etiologic Factors for Pediatric Acute Lymphoblastic Leukemia in Large Childhood Cancer Survivorship Cohorts.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology·2026
Same author

Impact of Dosing Interval Adherence on Pharmacokinetic Outcomes of Recombinant Erwinia Asparaginase in Pediatric Leukemia or Lymphoma.

Pharmacotherapy·2026
Same author

Correction: Pourroy et al. High-Dose Methotrexate at All Ages: Safety, Efficacy, and Outcomes from the HDMTX European Registry. <i>Cancers</i> 2026, <i>18</i>, 124.

Cancers·2026
Same author

Efficacy and Safety of Obinutuzumab in Active Systemic Lupus Erythematosus.

The New England journal of medicine·2026

相关实验视频

Updated: Jun 15, 2025

A Simple and Rapid Protocol to Non-enzymatically Dissociate Fresh Human Tissues for the Analysis of Infiltrating Lymphocytes
07:29

A Simple and Rapid Protocol to Non-enzymatically Dissociate Fresh Human Tissues for the Analysis of Infiltrating Lymphocytes

Published on: December 6, 2014

20.0K

瘤溶解综合征是什么?

Scott C Howard1,2,3, Anna Avagyan4, Biruh Workeneh5

  • 1Resonance, Memphis, TN, USA. Scott.Howard@ResonanceHealth.org.

Nature reviews. Disease primers
|August 22, 2024
PubMed
概括

瘤溶解综合征 (TLS) 是一种危险的瘤紧急情况,导致严重的代谢失衡. 早期检测和干预,包括水分和药物,如拉斯布里卡斯和阿洛普林醇,对于患者的生存至关重要.

更多相关视频

Neutrophil Extracellular Traps Generated by Low Density Neutrophils Obtained from Peritoneal Lavage Fluid Mediate Tumor Cell Growth and Attachment
08:59

Neutrophil Extracellular Traps Generated by Low Density Neutrophils Obtained from Peritoneal Lavage Fluid Mediate Tumor Cell Growth and Attachment

Published on: August 3, 2018

8.8K
Capture and Release of Viable Circulating Tumor Cells from Blood
08:10

Capture and Release of Viable Circulating Tumor Cells from Blood

Published on: October 28, 2016

8.5K

相关实验视频

Last Updated: Jun 15, 2025

A Simple and Rapid Protocol to Non-enzymatically Dissociate Fresh Human Tissues for the Analysis of Infiltrating Lymphocytes
07:29

A Simple and Rapid Protocol to Non-enzymatically Dissociate Fresh Human Tissues for the Analysis of Infiltrating Lymphocytes

Published on: December 6, 2014

20.0K
Neutrophil Extracellular Traps Generated by Low Density Neutrophils Obtained from Peritoneal Lavage Fluid Mediate Tumor Cell Growth and Attachment
08:59

Neutrophil Extracellular Traps Generated by Low Density Neutrophils Obtained from Peritoneal Lavage Fluid Mediate Tumor Cell Growth and Attachment

Published on: August 3, 2018

8.8K
Capture and Release of Viable Circulating Tumor Cells from Blood
08:10

Capture and Release of Viable Circulating Tumor Cells from Blood

Published on: October 28, 2016

8.5K

科学领域:

  • 在瘤学瘤学.
  • 腎臟病學 (nephrology) 是一種醫學專業.
  • 关键护理医学 关键护理医学

背景情况:

  • 瘤溶解综合征 (TLS) 是一种危及生命的瘤紧急情况.
  • 它的特点是瘤细胞的快速分解和细胞内内容的释放.
  • 导致严重的电解质异常和潜在的器官损伤.

研究的目的:

  • 总结TLS的病理生理学,风险和管理.
  • 强调监测和预防措施的重要性.
  • 讨论像拉斯布里卡斯和阿洛普林醇这样的具体干预措施的作用.

主要方法:

  • 对TLS现有文献的审查.
  • 对临床表现和风险因素的分析.
  • 讨论当前的治疗策略和新出现的问题.

主要成果:

  • TLS会导致高尿血,高血,高酸血,低血和山丁积.
  • 危险因素包括巨大的瘤负担和癌症治疗的开始.
  • 潜在的并发症包括急性损伤,心律失常和多器官衰竭.

结论:

  • 预防策略包括密切监测和补水.
  • 基于患者的风险,使用拉斯布里卡斯和阿洛普林醇等干预措施.
  • 在TLS管理中测量丁的临床实用性需要进一步研究.