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新辅助治疗后磁共振成像的预测价值:一个元分析

Yaniv Zager^1,2, Nir Horesh³, Michael Abdelmasseh^4,5

¹Colon and Rectum Surgery, Adventhealth, Orlando, FL, USA. Yaniv.zager.md@adventhealth.com.

Surgical endoscopy

|August 22, 2024

概括

对于直肠癌的新辅助疗法后的MRI恢复显示了与病理学的有限一致性. 这影响了临床决策,突出了对MRI进一步研究的需要.

科学领域:

在瘤学瘤学.
放射学放射学是一门学科.
胃肠病学胃肠病学

背景情况:

新辅助疗法是局部晚期直肠癌的标准,改善了结果.
磁共振成像 (MRI) 对于术前分期和治疗后重新分期至关重要.
评估MRI在新辅助疗法后重新分期的准确性对于治疗规划至关重要.

研究的目的:

在直肠癌患者中进行元分析,评估MRI重新分期和术后病理之间的一致性.
评估MRI在预测瘤和节点分期,CRM和pCR在新辅助治疗后的准确性.

主要方法:

一个符合PRISMA 2020指南的元分析.
在PubMed和谷歌学者系统搜索相关研究.
包括比较重新分期MRI与病理结局的研究,分析ypT,ypN,CRM和pCR.

主要成果:

分析了33项包括4100名患者的研究.
聚合一致率: ypT 阶段 63.9%, ypN 阶段 60.9%, pCR 70.4%,CRM 78.2%.
在大多数结果中观察到显著的异质性 (I2>80%).

结论:

恢复MRI与病理学对直肠癌的后辅助疗法的一致性是有限的.
临床决策应该考虑这些一致性限制.
在全新辅助疗法和免疫治疗后,需要对MRI的预测价值进行进一步的研究.

关键词:

这就是为什么MRI是MRI.新辅助剂是一种新辅助剂.这是直肠癌.在Restaging中使用Restaging.观察和等待,等待和等待.

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Magnetic Resonance Imaging

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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...