疲劳和抑郁症影响了多发性硬化症患者焦虑的患病率
Aliz Nyári1, Zsófia Kokas1, Szabolcs Szamosi1
1Department of Neurology, Albert Szent-Györgyi Faculty of Medicine and Clinical Center, University of Szeged, Szeged, Hungary.
概括
焦虑影响超过23%的匈牙利多发性硬化症患者,显着与疲劳,抑郁和疾病进展有关. 管理这些因素对于改善患者福祉至关重要.
科学领域:
- 神经学 神经学
- 精神病学是一个精神病学.
- 临床研究 临床研究
背景情况:
- 关于中东欧多发性硬化症患者焦虑患病率的数据有限.
- 了解焦虑与临床和人口因素的关联对于这一群体至关重要.
研究的目的:
- 确定匈牙利多发性硬化症 (pwMS) 患者焦虑的患病率.
- 分析与这种队列中的焦虑相关的临床人口统计因素.
主要方法:
- 260名匈牙利pwMS使用STAI-5焦虑问卷进行了评估.
- 评估疲劳 (FIS),抑郁症 (BDI-II),认知能力 (BICAMS) 和神经状态 (EDSS).
- 评估运动技能 (9洞钉测试) 和行走能力 (25英尺步行测试).
主要成果:
- 在23.1%的患者中发现了焦虑 (状态,特征或两者兼而有之).
- 疲劳和抑郁症与状态和特征焦虑都有很强的关联.
- 二次进展性多发性硬化症 (SPMS) 与状态焦虑有显著的关联.
结论:
- 在pwMS中,焦虑与疲劳,抑郁和二次进展性疾病形式有显著的关联.
- 这些发现凸显了多发性硬化症中精神病相关疾病的重大负担.
- 针对疲劳和抑郁症可能有助于缓解pwMS中的焦虑症状.
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