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晚间尿动频率与日本性结肠炎患者的临床结果之间的关联
Shogo Kitahata1, Shinya Furukawa2, Teruki Miyake3
1Department of Gastroenterology, Ehime Prefectural Central Hospital, Matsuyama, Ehime, Japan.
Neurourology and urodynamics
|August 23, 2024
概括
夜间尿动频率与性结肠炎 (UC) 患者的较差结果有关. 增加的夜间空洞可能表明粘膜愈合程度较低,这表明它可能是UC管理的有用临床信号.
科学领域:
- 胃肠病学 胃肠病学
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 临床医学 临床医学
背景情况:
- 夜尿,下泌尿道综合征 (LUTS) 的常见症状,经常在性结肠炎 (UC) 患者中观察到.
- 虽然LUTS和结直肠炎症之间存在关联,但UC患者夜间尿动频率的具体数据有限.
- 这项研究通过调查夜间尿动频率与UC的临床结果之间的关系来弥补这一差距.
研究的目的:
- 检查夜间尿动频率与日本性结肠炎 (UC) 患者的临床结果之间的关联.
- 确定夜间尿动频率是否与UC患者的粘膜愈合 (MH) 和临床缓解 (CR) 相相关.
主要方法:
- 一项针对287名日本UC患者的调查,使用自我管理的问卷.
- 根据夜间尿动频率,患者被分为三组:没有空洞,一个空洞,两个或更多的空洞.
- 使用多变量逻辑回归分析来评估夜间尿动频率与MH和CR的患病率之间的关联.
主要成果:
- 35.5%的患者经历了一次夜间空虚,而26.8%的患者经历了两次或更多.
- 粘膜愈合 (MH) 和临床缓解 (CR) 率分别为24.7%和59.2%.
- 两个或两个以上的夜间空洞独立地和反向地与MH相关 (调整后OR:0.31). 这种关联在非老年患者和CR患者中仍然显著.
结论:
- 夜间尿动频率与日本UC患者的粘膜愈合相反.
- 增加夜间尿动频率可以作为评估UC的粘膜愈合的补充临床指标.
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