时间限制的饮食,时钟在幕后滴答滴答
Aleix Ribas-Latre1,2,3, Sonia Fernández-Veledo1,2,3, Joan Vendrell1,2,3
1Institut d'Investigació Sanitària Pere Virgili (IISPV), Hospital Universitari de Tarragona, Tarragona, Spain.
Frontiers in pharmacology
|August 23, 2024
概括
时间限制饮食 (TRE) 在肥胖中显示出对代谢健康的前景. 这篇评论探讨了TRE.
科学领域:
- 代谢健康 代谢健康
- 肥胖问题研究研究
- 营养科学 营养科学
背景情况:
- 代谢平衡需要在食和禁食期间进行营养循环.
- 肥胖和代谢障碍与营养调节受损有关.
- 卡路里限制 (CR) 和间歇性禁食 (IF) 是改善代谢健康的策略.
研究的目的:
- 审查各种间歇性禁食 (IF) 方法的代谢影响,重点是时间限制饮食 (TRE).
- 综合当前关于TRE对肥胖和代谢健康的影响的知识,考虑时间型和昼夜节律.
- 为了确定TRE干预的研究差距.
主要方法:
- 叙事审查方法.
- 对临床前和临床研究进行系统的文献搜索.
- 关键词包括: 肥胖, 间歇性禁食, 时间限制的饮食, 时代型, 循环节律.
主要成果:
- 在超重,肥胖和II型糖尿病患者中,TRE干预显示了代谢益处.
- 动物模型突出了昼夜时钟在缓解因肥胖引起的代谢干扰中的作用,并通过时间限制的养 (TRF) 进行了制.
- TRE可以调节微生物群,影响昼夜节律.
结论:
- TRE是一种有前途的IF策略,用于改善代谢健康和控制肥胖.
- 个体时刻型对TRE疗效起着至关重要的作用,在实践中经常被忽视.
- 昼夜钟,微生物群和TRE之间的相互作用需要进一步研究.
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