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移植患者的激进前列腺切除术-一个多中心体验
Jacob Schmidt1, Abdulbaki Yakac2, Robert Peters1
1Department of Urology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
European urology open science
|August 23, 2024
概括
激进前列腺切除术是移植患者局部前列腺癌的安全和可行的治疗方法,显示了可接受的瘤结果. 需要仔细查,以避免在这个人群中出现不足的情况.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 移植手术 移植手术
- 在瘤学瘤学.
背景情况:
- 移植接受者 (KTRs) 面临更高的生殖尿道癌症的风险,包括前列腺癌 (PCa).
- 预计KTR人口老龄化会增加PCa的流行率.
- 了解KTR中PCa的手术结果至关重要.
研究的目的:
- 评估脏移植接受者的急性前列腺切除术 (RP) 的安全性和瘤结果.
- 为了在KTR中比较开放式RP与机器人辅助RP (RARP) 的外科手术前期和长期结果.
主要方法:
- 在2006-2023年期间,在9个中心进行了62个KTR进行RP的回顾性分析.
- 使用Clavien-Dindo分类来评估并发症.
- 用于生存分析的卡普兰-梅尔方法 (OS,BRFS,移植生存率).
主要成果:
- 在RP后没有发生移植损失.
- 50%的患者没有术后并发症;14.5%的患者有3级以上的并发症.
- 平均整体存活期为128个月; 平均生化无复发存活期为106个月.
结论:
- 在KTRs中,RP是局部PCa的可行和安全的治疗方法.
- 观察到可接受的瘤结局.
- 建议对PCa的KTR进行加强的低阶段查.
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