身体圆度指数和骨矿物质密度之间的负相关性:来自NHANESES的见解
Ziyao Ding1,2, Zhe Zhuang1,2, Rongze Tang1,2
1Department of Spine Surgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China.
Frontiers in nutrition
|August 23, 2024
概括
较高的身体圆度指数 (BRI) 与较低的骨矿物密度 (BMD) 有关,从而增加骨质疏松症的风险. 这项研究强调了BRI作为早期骨质疏松症干预的潜在标志物.
科学领域:
- 老年学是指老年学的学科.
- 公共卫生 公共卫生
- 身体组成分析 身体成分分析
背景情况:
- 骨质疏松症 (OP) 是一种全球性退行性骨病,其特征是骨矿物质密度 (BMD) 降低和骨脆弱性增加.
- 传统的指标可能无法完全捕捉身体脂肪分布对骨健康的影响.
- 身体圆度指数 (BRI) 为评估身体脂肪分布提供了一种新型的人类测量方法.
研究的目的:
- 研究美国成年人身体圆度指数 (BRI) 与骨矿物质总密度 (BMD) 之间的关联.
- 为了确定BRI是否可以作为骨质疏松风险的指标.
主要方法:
- 利用了2011-2018年国家健康和营养检查调查 (NHANES) 9,295名参与者的数据.
- 使用双能X射线吸收计 (DXA) 测量骨矿物质密度 (BMD).
- 从腰围和身高计算的身体圆度指数 (BRI),采用加权多变量线性回归和平滑曲线拟合.
主要成果:
- 在BRI和总 BMD (P < 0.0001) 之间观察到一个显著的反向关系.
- 每个单位增加的BRI与0.0313g/cm2的总BMD下降相关.
- 在BRI=9.5229的拐点表明,超过这个值后,骨质量减少更明显.
结论:
- 较高的BRI与较低的总骨质量相关,这表明骨质疏松症的风险增加.
- BRI与BMD的关联凸显了身体脂肪分布在骨质疏松症预防中的重要性.
- 在骨质疏松症管理中,BRI可以作为早期干预策略的有价值标记.
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