下血瘤对第一季度母亲血清中自由β-hCG和PAPP-A水平的影响
Arife Akay1,2, Yıldız Akdaş Reis1, Büşra Şahin1,3
1Etlik Zübeyde Hanım Maternity and Women's Health Teaching and Research Hospital Department of Obstetrics and Gynecology Ankara Turkey Etlik Zübeyde Hanım Maternity and Women's Health Teaching and Research Hospital, Department of Obstetrics and Gynecology, Ankara, Turkey.
概括
腹腔下血腫 (SH) 不會影響孕婦血清中與懷孕相關的血蛋白-A (PAPP-A) 和自由β-人腹腔性淋巴激素 (β-hCG) 的水平. 这些标志物仍然可靠,用于第一季度形形状查,威胁流产 (TM) 病例与SH.
科学领域:
- 生殖医学 生殖医学
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 生物化学 生物化学
背景情况:
- 胸下血腫 (SH) 是懷孕早期常見的發現,通常與可能流產 (TM) 相關.
- 第一个三个月的母体血清标志物,包括PAPP-A和自由β-hCG,对于查胎儿积症至关重要.
- 对于SH对这些查标记物的影响尚未完全理解.
研究的目的:
- 调查下血瘤 (SH) 对第一季度孕妇血清PAPP-A和自由β-hCG水平在怀孕中可能流产 (TM) 的影响.
- 为了确定PAPP-A和自由β-hCG作为查标记物的可靠性,在由SH复杂的TM病例中.
主要方法:
- 从2015年至2021年期间,从2015年至2021年之间具有和没有SH的TM病例数据的回顾性分析.
- 人口特征,产科史和超声波发现的比较.
- 在研究组 (含SH) 和对照组 (不含SH) 之间对第一季度PAPP-A和自由β-hCG水平 (MoM值) 的统计分析.
主要成果:
- 总共分析了119个SH病例和153个对照病例.
- 两组之间PAPP-A (0.88对0.90,p=0.519) 和自由β-hCG (1.04对0.99,p=0.66) 的中位数MoM值没有显著差异.
- 多变量分析显示,SH尺寸和标记水平之间没有显著的关系.
结论:
- 腹腔下血液瘤 (SH) 在妊娠的第一季度不会显著改变母亲血清中PAPP-A和自由β-hCG的水平.
- PAPP-A和自由β-hCG可可靠地用于SH威胁性流产 (TM) 病例的胎儿动质查.
关键词:
堕胎,受到威胁的堕胎.形积分症 (Aneuploidy) 是一个生物标志物 生物标志物胆管性淋巴激素是一种胆管性淋巴激素.怀孕第一季度 怀孕第一季度与怀孕相关的血蛋白-A.在底血腫 (subchorionic hematoma) 的情況下,更多相关视频
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