与肠道准备进行结肠镜检查相关的急性胃病
Su Bee Park1, Moonhyung Lee1, Min Seob Kwak1
1Department of Internal Medicine, Kyung Hee University Hospital at Gang Dong, College of Medicine, Kyung Hee University, Seoul, Korea.
概括
口服硫酸盐片 (OST) 显示出更高的多和腺瘤检测,但与1L聚乙烯甘醇与酸 (1L PEG/Asc) 肠道制剂相比,与急性胃病增加有关.
科学领域:
- 胃肠病学 胃肠病学
- 内镜检查是指内镜检查.
- 药理学 药理学是指药理学的学科.
背景情况:
- 低容量肠道准备剂可以提高患者对结肠镜检查的遵守性.
- 对肠道制备剂的胃安全数据仍然有限.
- 与这些药物相关的急性胃需要彻底评估.
研究的目的:
- 评估和比较与两种肠道制备剂相关的急性胃病: 1 L 聚乙烯甘醇与酸 (1 L PEG/Asc) 和口服硫酸盐片 (OST).
主要方法:
- 一个回顾性研究,比较健康的受试者接受食管胃管腺镜检查 (EGD) 和结肠镜检查.
- 对1L PEG/Asc和OST组的患者特征,肠道准备成功率,急性胃病和聚/腺瘤检测率的评估.
主要成果:
- OST和1L PEG/Asc都显示出类似的肠道清洗成功率.
- OST组显示出显著更高的聚和腺瘤检测率 (p<0.001和p=0.013).
- OST组的急性胃粘膜病变发生率显著更高,包括侵蚀和红斑 (所有p<0.001),以及更高的Lanza分数 (1.3比0.4,p<0.001).
结论:
- 口服硫酸盐片 (OST) 与1L的PEG/Asc.相比,与急性胃病有显著的相关性.
- 由于胃风险增加,医生应仔细考虑在同时接受EGD和结肠镜查的患者中使用OST.
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