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相关概念视频

Hallucinogens and Psychedelics01:27

Hallucinogens and Psychedelics

160
Hallucinogens are psychoactive substances that profoundly alter perceptual experiences, generating unreal visual and sensory images. Often referred to as psychedelic drugs — a term derived from the Greek words "psyche" (mind) and "delos" (revealing) — these substances include marijuana and lysergic acid diethylamide (LSD), among others. These drugs vary in intensity and effects.
Marijuana, derived from the dried leaves and flowers of the hemp plant, contains...
160
CNS Stimulants: Psychedelic Agents01:22

CNS Stimulants: Psychedelic Agents

133
Hallucinogens, also known as psychedelic drugs, are a class of substances known for their ability to alter perception, cognition, and emotions. Despite their profound effects on the mind, these drugs are non-addictive, setting them apart from many other abused substances. The mechanism of action of these drugs lies in their impact on the 5-HT2A receptor in the brain. Upon activation, this receptor couples to Gq-type G proteins, triggering a cascade that releases intracellular calcium. This...
133

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相关实验视频

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Rapid High-throughput Species Identification of Botanical Material Using Direct Analysis in Real Time High Resolution Mass Spectrometry
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根据频率和数量确定三种psilocybin使用模式.

Bethany A Gray1, Olivia L Bolts1, Deborah Fidler2

  • 1Department of Psychology, Colorado State University, Fort Collins, Colorado.

Journal of studies on alcohol and drugs
|August 23, 2024
PubMed
概括

这项研究确定了三种不同的psilocybin使用模式:破片器,片器和微剂量器. 这些模式在频率和剂量上有所不同,在非临床西使用者中观察到相关的人口差异.

科学领域:

  • 精神活性物质研究 精神活性物质研究
  • 行为心理学 行为心理学
  • 神经科学是一个神经科学.

背景情况:

  • 非临床的psilocybin使用模式没有得到充分的记录.
  • 松素的使用从不频繁的高剂量 (宏) 到频繁的低剂量 (微) 不同.
  • 了解这些模式对于公共卫生和减少危害至关重要.

研究的目的:

  • 根据自我报告的频率和数量,识别出不同的西使用模式.
  • 描述与每个已识别的西使用模式的人口统计学关联.

主要方法:

  • 隐藏的个人资料分析被用来辨别psilocybin使用模式.
  • 参与者 (N=664) 来自在线社区.
  • 模式是由典型的使用频率和数量来定义的.

主要成果:

  • 确定了三种不同的psilocybin使用配置文件:破碎器 (18%),tripper (64%) 和微剂量器 (18%).
  • "芯片"型号涉及1至4次年度使用 (0.75至1.0g),"三次使用"涉及2至6次年度使用 (2至4g),而"微剂量"涉及频繁使用 (2至4次/周) 以较低剂量 (0.25至0.75g).
  • 个人资料在人口统计学,终身使用和psilocybin消费时间方面有所不同.

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结论:

  • 非临床的 псилоцибин使用是异质的,具有可识别的模式.
  • 结果出现了三种不同的配置文件 (chipper,tripper,microdoser),根据使用频率,数量和人口统计区分开来.
  • 未来的研究应该探索影响使用结果和变异性的因素.