基于真实世界的研究,评估NiaoDuQing颗粒对慢性病的治疗效果
Rui Sun1,1, Jianfeng Hao1,1, Qian Li2
1The First Affiliated Hospital of Anhui University of Science and Technology (The First People's Hospital of Huainan), Huainan, China.
概括
在慢性病患者中,NiaoDuQing颗粒显示出长期益处,在18个月内显著改善了EGFR和尿酸水平等关键指标.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 传统中国医药 传统中国医药
- 药理学 药理学是指药理学的学科.
背景情况:
- 杜青颗粒是一种中国草药,已获批准用于慢性病 (CKD) 治疗.
- 它在中国已有20多年的临床使用.
- 关于其在CKD患者的长期疗效的文献有限.
研究的目的:
- 综合评估NiaoDuQing粒子 (NDQP) 对CKD患者的长期治疗效果.
- 分析临床数据,评估NDQP对CKD进展和生物标志物的影响.
- 提供NDQP在治疗慢性病中的持续益处的证据.
主要方法:
- 一项涉及148名患有各种类型的CKD的参与者的研究.
- 收集和分析人口统计数据,CKD分类和诊断指标.
- 在3,6,9,12和18个月的治疗效果的纵向监测.
主要成果:
- 平均eGFR在3,6,9,12和18个月显著增加 (P<0.05).
- 尿酸和尿素的平均水平在3,6,9,12,18个月显著下降 (P<0.05).
- 到第6个月,平均肌素水平显著下降 (P<0.05).
结论:
- 杜颗粒在治疗慢性病患者中表现出持续的疗效,长达18个月.
- NDQP显著改善了包括eGFR,尿酸和尿素在内的关键诊断指标.
- 这些发现支持使用NiaoDuQing颗粒用于长期CKD管理.
更多相关视频
08:15Author Spotlight: Network Pharmacology and Molecular Docking to Decipher the Action of Jiawei Shengjiang San Against Diabetic Kidney Disease
Published on: May 10, 2024
524
14:18Author Spotlight: Investigating the Potential of Chinese Herbal Medicinal Active Dioscin in Treating IgA Nephropathy
Published on: October 13, 2023
1.7K
相关概念视频
01:11Renal Failure: Dose Adjustments
71
In patients with renal impairment, drugs undergo significant changes in their pharmacokinetics, which require dosage adjustments to ensure safe and effective therapy.
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
71
01:17Factors Affecting Renal Clearance: Renal Impairment
62
Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
62