下调miR-432-5p通过激活RTN3信号通路来加剧阿德里亚米辛诱导的心脏毒性

Wei Geng1, Shaohua Yan1, Dasen Sang1

  • 1Department of Cardiology, Baoding No.1 Central Hospital, Baoding, Hebei Province, China.

Aging
|August 23, 2024
PubMed
概括

阿德里亚米 (ADR) 化学疗法通过减少miR-432-5p和损害线粒体功能而导致心脏毒性. 恢复miR-432-5p通过降低ER压力和RTN3通路的调节来保护心脏.

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