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类似于氨酸的晶状体局部化到非新形成的真实声带和附件
Melad N Dababneh1, Alton B Farris2, Scott M Steward-Tharp2
1Department of Pathology, Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, AL, USA.
Head and neck pathology
|August 23, 2024
概括
富含氨酸的结晶体 (TC) 存在于非新生体的喉组织中,主要是前部结晶体. 它们的存在可能与机械压力或衰老有关,而不是放射治疗.
科学领域:
- 喉腔病理学 喉腔病理学
- 病理学 病理学 病理学
- 历史学 历史学 历史学
背景情况:
- 富含氨酸的晶体化物 (TC) 通常存在于唾液腺形腺瘤中.
- 它们在非新发性喉组织中的存在是罕见的,以前只在喉中报告.
- 这项研究调查了全喉切除样本中TC的频率和位置.
研究的目的:
- 为了确定在非新发性喉组织中丰富的氨酸结晶体 (TC) 的发生和解剖分布.
- 探索TC存在与患者人口统计,诊断和放射治疗史等因素之间的潜在关联.
主要方法:
- 进行了对86个连续的全喉切除试样的审查.
- 检查了声和前面的指导部的偏部分.
- 收集了患者人口统计,诊断,辐射史和TC存在/位置的数据.
主要成果:
- 在16个喉腔切除标本中 (19%) 发现了富含氨酸的结晶体 (TC).
- 最常见的TC位于前面的指挥部 (81.25%).
- 显微镜检查显示TC在前面的黄斑,声带和前面的委托肌.
结论:
- 富含氨酸的晶体化物 (TC) 可以出现在非新发性喉组织中,与新发症不同.
- 在TC的存在和之前的放射治疗之间没有明确的关联.
- 结结形成可能与机械应力或喉连接组织与年龄相关的变化有关.
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