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Updated: Jun 15, 2025

Transfer of Manipulated Tumor-associated Neutrophils into Tumor-Bearing Mice to Study their Angiogenic Potential In Vivo
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通过限制树突细胞数量和功能,TNFR1信号促进胰腺瘤的生长

Muhammad S Alam1, Matthias M Gaida2, Hagen R Witzel3

  • 1Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

Cell reports. Medicine
|August 23, 2024
PubMed
概括

在胰腺癌中准瘤亡因子受体1 (TNFR1) 增强T细胞活性,减缓瘤生长. 阻断TNFR1增加了有益的树突细胞 (DC),提供了一个有前途的治疗策略.

关键词:
在KPC小鼠.我们的PDAC是PDAC.这就是TNF-α.这就是TNFR1的特点.灭症 (apoptosis) 是一种死亡的过程.树突细胞是一种树突细胞.这是一种炎症炎症炎症炎症.胰腺腺癌的癌症.

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