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Updated: Jun 15, 2025

Structural Biology and Analytical Chemistry Approaches for Characterizing C-Glycoside Metabolic Enzymes in Human Gut Microbiota
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一个截断的人类GlcNAc-1-phosphotransferase变体的结构揭示了其过活性的基础

Hua Li1, Balraj Doray2, Benjamin C Jennings2

  • 1Department of Structural Biology, Van Andel Institute, Grand Rapids, Michigan, USA.

The Journal of biological chemistry
|August 23, 2024
PubMed
概括

失去GlcNAc-1-转化酶 (PTase) 会导致II型粘脂症. 这项研究揭示了一种过度活跃的PTase变体的冷-EM结构,详细介绍了其催化核心和相互作用,这对于了解 lysosomal酶向至关重要.

关键词:
国内生产总值 (GNP) 的增长这就是 GlcNAc-1-phosphotransferase 的作用.冰冷-EM,结构生物学酶活性的酶活动.酶催化酶的催化作用飞飞的光转移酶人类的光转移酶.曼诺-6-酸盐准系统第二种粘脂症II蛋白质结构 蛋白质结构

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