[在利布雷维尔,加的广泛和广泛的耐药结核病]
U D Kombila1, C Manomba Boulingui2, F N'Gomanda3
1Service de médecine interne, CHU de Libreville, faculté de médecine, université des sciences de la santé de Libreville, Libreville, Gabon; Faculté de médecine, université des sciences de la santé de Libreville, Libreville, Gabon.
Revue des maladies respiratoires
|August 23, 2024
概括
广泛耐药性结核病 (XDR) 和广泛耐药性结核病 (XDR) 是加面临的重大挑战. 由于高死亡率,早期检测和治疗至关重要,特别是在来自不利地区的新病例中.
科学领域:
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
- 微生物学 微生物学
背景情况:
- 在加对广泛耐药 (XDR) 结核菌菌菌株的研究有限.
- 多药耐药结核病 (MDR-TB) 构成越来越大的威胁,需要流行病学监测.
研究的目的:
- 在加调查XDR前和XDR结核病的流行病学.
- 分析MDR-TB患者的治疗结果和随着时间的推移而发生的变化.
主要方法:
- 在Nkembo抗肺结核中心进行了回顾性研究,分析了2019-2022年的数据.
- 纳入标准侧重于XDR前和XDR-TB的患者.
主要成果:
- 确定了15名患者,11名 (73.3%) 患有前XDR-TB,4名 (26.7%) 患有XDR-TB.
- 53.3%是新的病例,60%居住在贫困地区.
- 治疗成功率为前XDR-TB的36.4%,XDR-TB的50.0%,死亡率为33.3%,主要是在头三个月内.
结论:
- 初级XDR前结核病的高发病率凸显了广泛的耐药性.
- 迫切需要加强接触者追踪和迅速启动治疗.
- 公共卫生战略必须解决导致结核病传播的社会经济因素.
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