接受脏移植的接受者在有和没有延迟移植功能的情况下的再接收结果
Rachana Punukollu1, Alex Nica2, Stephanie Ohara1
1Division of Transplant Surgery, Mayo Clinic, Phoenix, Arizona.
Transplantation proceedings
|August 23, 2024
概括
患有移植后移植功能的延迟 (DGF) 的患者有更高的再入院风险. 然而,DGF没有影响最初的移植或患者存活率,尽管多次再接收降低了移植存活率.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 移植医学 移植医学
- 免疫学 免疫学 免疫学
背景情况:
- 延迟移植功能 (DGF) 是移植后的常见并发症.
- DGF与医疗保健资源利用率的增加有关.
- 了解DGF对再接收和长期结果的影响至关重要.
研究的目的:
- 为了比较DGF和没有DGF的脏移植接受者的再入院率和移植后的结果.
- 在GDF的背景下,确定影响再接收的因素.
主要方法:
- 已故捐赠移植受体 (2015-2020) 的回顾性审查.
- 纳入标准:移植后至少有一次早期再入院的接受者.
- 两个组的比较:需要再接收的DGF接收者与不需要再接收的DGF接收者.
主要成果:
- 接收DGF的受益者有明显更高的早期再接收率 (43.9%与29.1%相比).
- 再入院的DGF接受者有更多的门诊访问,并且更有可能有多次再入院.
- 在将DGF与不需要再入院的DGF接受者进行比较时,在初始住院时间或患者/死亡审查的移植存活率上没有差异.
结论:
- 延迟的移植功能增加了移植后再入院的风险.
- 虽然DGF本身不会立即影响存活率,但在DGF患者中,多次再接收与较低的死亡审查移植存活率相关.
- 减少DGF患者再入院和感染的策略是有必要的.
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