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Updated: Jun 15, 2025

HOX Loci Focused CRISPR/sgRNA Library Screening Identifying Critical CTCF Boundaries
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Published on: March 31, 2019

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通过CTCF依赖的物理绝缘和促进竞争的合作隔离监管领域的合作隔离

Thais Ealo1, Victor Sanchez-Gaya2, Patricia Respuela1

  • 1Institute of Biomedicine and Biotechnology of Cantabria (IBBTEC), CSIC/Universidad de Cantabria, Santander, Spain.

Nature communications
|August 23, 2024
PubMed
概括

发育基因和CTCF位点合作隔离调节领域,确保精确的基因表达. 这项研究揭示了CTCF网站提供物理绝缘,而基因使用促进者竞争进行监管绝缘.

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