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Updated: Jun 15, 2025

Performing Data Mining And Integrative Analysis Of Biomarker in Breast Cancer Using Multiple Publicly Accessible Databases
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使用Pathway Ensemble工具和基准来无偏见地发现癌症途径和治疗方法

Luopin Wang1,2, Aryamav Pattnaik2,3, Subhransu Sekhar Sahoo2,3

  • 1Department of Computer Science, Purdue University, West Lafayette, IN, USA.

Nature communications
|August 23, 2024
PubMed
概括

本研究介绍了Benchmark和Pathway Ensemble工具 (PET),用于识别与疾病相关的生物途径. 由于PET的性能优于现有的方法,有助于发现生物标志物和开发各种癌症的治疗策略.

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Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
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