集群头痛的尾神经刺激:从"电压调器"中学到的教训
Linda Kollenburg1, H Arnts2, M Heitkamp3
1Department of Neurosurgery, Radboud University Medical Center, Geert Grooteplein Zuid 10, Nijmegen, 6525 GA, Netherlands. Linda.Kollenburg@radboudumc.nl.
The journal of headache and pain
|August 23, 2024
概括
对于集群头痛 (CH) 的尾神经刺激 (ONS) 中的电压调节可能有助于管理发作. 这种行为在近一半的患者中见到,为ONS作为耐药性CH的急性治疗提供了潜力.
科学领域:
- 神经学 神经学
- 神经外科 神经外科
- 疼痛管理 疼痛管理
背景情况:
- 集群头痛 (CH) 显著影响患者,并且经常抵御传统治疗.
- 尾神经刺激 (ONS) 是治疗耐药性CH的有效选择.
- 一部分患有ONS的CH患者表现出"电压调节"行为,通过遥控器调整振幅,可能与焦虑和自我控制有关.
研究的目的:
- 研究在接受ONS的CH患者中电压调节的发生和有效性.
- 探索电压调节行为背后的特征和患者报告的理由.
主要方法:
- 对接受双边ONS (2020-2024) 的CH患者的回顾性分析.
- 收集关于攻击频率,强度和持续时间的数据.
- 展望面试评估了与电压调节相关的响应,频率,持续时间,理由,感觉和振幅变化.
主要成果:
- 在1年的随访中,ONS的整体响应率为70%.
- 48%的患者被确定为电压调器.
- 电压调整涉及到振幅的增加 (例如. 92%),每月发生1-20次,持续20分钟至48小时,带有刺痛/刺痛的感觉.
结论:
- 在ONS中调节电压可能有助于停止或终止CH攻击.
- 这种行为表明ONS作为耐药性CH的急性治疗的潜力.
- 对电压调节的进一步研究可以优化ONS的有效性并改善CH患者的生活质量.
相关概念视频
Spinal Cord: Information Processing
The spinal cord is an integral hub for motor and sensory information that enables the brain to communicate with the peripheral nervous system (PNS). This communication consists of relaying sensory data and transmission of motor commands.
Sensory Information Processing
Sensory information processing begins at the sensory receptors located in the skin and other tissues, which detect somatic sensory stimuli such as touch, temperature, or pain. These receptors function as catalysts, initiating...
Sensory Information Processing
Sensory information processing begins at the sensory receptors located in the skin and other tissues, which detect somatic sensory stimuli such as touch, temperature, or pain. These receptors function as catalysts, initiating...
Peripheral Nervous System: Ganglia and Nerves
The Peripheral Nervous System (PNS) is a crucial component of the body's neural network, extending beyond the central nervous system (CNS) to bridge the gap between the CNS and the external environment. It encompasses nerves, ganglia, and sensory receptors.
Nerves
The nerve is a bundle of axons that serves as the communication highway in the PNS. Each nerve is ensheathed in a protective layer of connective tissue called the epineurium. This outermost layer safeguards the nerve and supports the...
Nerves
The nerve is a bundle of axons that serves as the communication highway in the PNS. Each nerve is ensheathed in a protective layer of connective tissue called the epineurium. This outermost layer safeguards the nerve and supports the...
Sympathetic Pathways: Sympathetic Chain Ganglia
The sympathetic chain ganglia, also known as the sympathetic trunk ganglia or paravertebral ganglia, are a series of ganglia located bilaterally on either side of the spinal column. These ganglia serve as relay stations for the sympathetic nervous system. Preganglionic neurons originating in the spinal cord project their axons to the sympathetic chain ganglia. Within the ganglia, these preganglionic fibers synapse with postganglionic neurons.The postganglionic neurons of the sympathetic trunk...
Pain
Pain serves as a critical warning signal that alerts the body to potential or actual harm. When mechanical pressure on the skin is intense, such as from a sharp pinch, the sensation transitions from touch to pain. Similarly, extreme temperatures, like a hot pot handle, convert the sensation of heat into pain. Pain can also result from overstimulation of other senses, such as blinding light, loud noise, or the intense heat from habañero peppers. This ability to sense pain is essential for...


