超加工食品与骨质疏松症之间的关联:基于NHANES数据库的横截面研究
Songfeng Wang1, Jiasi Xie1, Dandan Zhai1
1Department of Oncology, The First Medical Center of Chinese People's Liberation Army General Hospital, Chinese People's Liberation Army Medical School, No. 28 Fuxing Road, Haidian District, Beijing, 100853, P.R. China.
Nutrition & metabolism
|August 23, 2024
概括
高度超加工食品 (UPF) 摄入量与较低的骨矿物质密度 (BMD) 和骨质疏松症风险增加有关. 身体活动可能会调解这种关联,提供一种潜在的生活方式干预.
科学领域:
- 营养科学 营养科学
- 骨健康研究 骨健康研究
- 公共卫生 公共卫生
背景情况:
- 超加工食品 (UPF) 含有营养特征和添加剂,影响骨健康.
- 身体活动是一种可修改的生活方式因素,可能会影响骨矿物质密度 (BMD).
- 在UPF消费,体力活动和骨质疏松症风险之间的相互作用仍然不完全理解.
研究的目的:
- 调查超加工食品 (UPF) 摄入量与骨质疏松症之间的关联.
- 探索体育活动和其他因素在UPF-骨质疏松症途径中的调解作用.
主要方法:
- 从国家健康和营养检查调查 (NHANES) 中对成年人数据的横截面分析.
- 线性和后勤回归模型评估了食品类别 (包括UPF) 与骨质疏松/骨质疏松之间的关联.
- 对体力活动和相关因素进行了子组分析和调解/相互作用效应评估.
主要成果:
- 增加的UPF摄入量与部部和全骨BMD (β=-0.003) 的降低相关.
- 较高的UPF消费 (>>57.51%) 与骨质疏松症的几率增加有关 (OR=1.789).
- 身体活动对UPF与骨质疏松症的关系表现出中介作用 (OR=0.47,21.54%的中介作用).
结论:
- 超加工食品 (UPF) 的摄入量与骨矿物质密度 (BMD) 的降低和骨质疏松症的更高患病率显著相关.
- 身体活动表现出互动和调解效应,表明在UPF消费和骨健康的背景下具有保护作用.
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