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结构变化对椎间盘低应变率行为的影响
Samantha Hayward1, Patrick S Keogh1, Anthony W Miles1
1Department of Mechanical Engineering, University of Bath, Bath, UK.
概括
改变椎间盘 (IVD) 的核脉 (NP) 显著改变脊柱力学. 这些结构变化增加了硬度和能量吸收,可能导致周围脊柱结构承受更大的负荷.
科学领域:
- 生物力学 生物力学
- 脊柱力学 脊柱力学 脊柱力学
- 整形外科的研究研究.
背景情况:
- 脊椎间盘 (IVD),包括纤维环 (AF) 和脉核 (NP),对于消散脊柱负荷至关重要.
- 了解NP对IVD机制的孤立贡献对于脊柱健康至关重要.
研究的目的:
- 在IVD中隔离NP的机械贡献.
- 调查NP极端结构变化对IVD机械行为的影响.
主要方法:
- 六个猪腰部IVD标本在六个自由度 (6DOF) 中进行了测试.
- 在低张力速度下,样本承受了400N的轴前负荷.
- 机械性能在三个条件下进行了评估:完好无损 (IN),完全核切除 (NN) 后,以及在骨质水泥注入核空隙 (SN) 后.
主要成果:
- 与完整的磁盘相比,核切割 (NN) 和水泥注入 (SN) 显著增加了线性刚度,负载范围和中侧曲和曲延伸的总能量.
- 在SN条件下,轴向压缩延伸的总能量增加,在大多数轴上弹性能量贡献减少.
- 这些变化表明体内周围脊柱结构的负荷增加.
结论:
- 细胞核的极端结构变化显著影响椎间盘机制.
- 在NP的变化可以导致增加硬度和改变能量消散,可能增加压力对邻近的脊柱部件.
- 需要进一步的研究,以充分阐明这些生物力学变化的体内影响.
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