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Updated: Jun 15, 2025

Direct Restart of a Replication Fork Stalled by a Head-On RNA Polymerase
07:27

Direct Restart of a Replication Fork Stalled by a Head-On RNA Polymerase

Published on: April 29, 2010

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在S阶段晚期复制分叉停滞导致DNA不匹配修复的新生链退化

Erica Colicino-Murbach1, Caitlin Hathaway1, Huzefa Dungrawala1

  • 1Department of Molecular Biosciences, University of South Florida, Tampa, FL, USA.

Nucleic acids research
|August 24, 2024
PubMed
概括

新合成的DNA在早期复制过程中受到保护,但在S阶段晚期停滞的分叉中降解,影响异色染色体的稳定性. 这个过程涉及特定的核酶,并受到染色质结构和DNA修复途径的影响.

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G2-seq: A High Throughput Sequencing-based Technique for Identifying Late Replicating Regions of the Genome06:40

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