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相关概念视频

Bone Disorders01:29

Bone Disorders

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Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
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Nature and Nurture01:10

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Many human characteristics, like height, are shaped by both nature—in other words, by our genes—and by nurture, or our environment. For example, chronic stress during childhood inhibits the production of growth hormones and consequently reduces bone growth and height. Scientists estimate that 70-90% of variation in height is due to genetic differences among individuals, and 10-30% of variation in height is due to differences in the environments that individuals experience,...
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Respiration is a crucial physiological function involving exchanging oxygen (O2) and carbon dioxide (CO2) between an organism and its environment. Various factors can impact this essential process:
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相关实验视频

Updated: Jun 15, 2025

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
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儿童的骨年龄发育随着高度的增加而延迟:一项多中心研究.

Qixing Liu1,2, Cidan Wangjiu3, Tudan Awang4

  • 1Department of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China.

The British journal of radiology
|August 24, 2024
PubMed
概括

高海拔可能会独立地延迟儿童的骨年龄 (BA) 发育. 这项研究揭示了海拔高度对BA的影响,强调在高海拔地区儿童的评估中考虑它的考虑.

关键词:
骨头年龄 骨头年龄在西藏藏语中,藏语是藏语的.高度的高度高度的高度.预测的年龄差异.

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科学领域:

  • 儿科内分泌学 儿科内分泌学
  • 骨的发育 骨的发育
  • 环境健康 环境健康

背景情况:

  • 骨龄 (BA) 评估对于评估儿科生长和发育至关重要.
  • 环境因素,如海拔高度,可能会影响骨成熟.
  • 关于高海拔对儿童骨年龄的具体影响的研究有限.

研究的目的:

  • 为了研究居住在不同高度的儿童的骨年龄 (BA) 特性.
  • 确定地理高度对儿童BA发展的独立影响.
  • 确定高度与预测年龄差 (PAD) 之间的关系,这是增长延迟或进步的指标.

主要方法:

  • 从2014年6月到2022年7月,对1318名儿童的左手腕放射图进行了回顾性分析.
  • 预测年龄差异 (PAD) 在三个海拔群体的比较:北京 (海拔43.5米),拉萨 (海拔3650米) 和纳奎 (海拔4500米).
  • 线性回归建模以评估海拔高度对PAD的影响,控制年龄,性别和种族.

主要成果:

  • 总共分析了1284名儿童,在北京的PAD值为0.1年,在拉萨的PAD值为-0.40年,在Nagqu的PAD值为-1.42年.
  • 线性回归证实了高度和PAD之间的显著负相关性 (拉萨系数 = -0.57,P <.001;Nagqu系数 = -1.55,P <.001).
  • 较高的海拔高度与骨年龄相对于时间年龄的较大延迟有关.

结论:

  • 高海拔似乎是一个独立的因素,有助于延迟儿童骨年龄的发展.
  • 这些发现强调了在评估儿科患者骨龄时考虑居住高度的重要性.
  • 这项研究提供了关于高海拔环境对儿童骨成熟的影响的新见解.