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基于人群药动力学研究的交互剂量优化器,用于指导中国骨髓瘤患者的甲铁酸剂量

Yanjie Zhang1, Xiemin Qi1, Xiaohui Huang1

  • 1Department of Clinical Pharmacy, State Key Laboratory of Analytical Chemistry for Life Science and Jiangsu Key Laboratory of Molecular Medicine, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210002, China.

Cancer chemotherapy and pharmacology
|August 24, 2024
PubMed
概括

这项研究开发了一个人群的药理动力学模型和一个剂量优化器,用于高剂量甲状腺酸盐 (HD-MTX) 在骨髓瘤患者. 该工具通过估计个体的药理动力学参数来帮助个性化HD-MTX治疗,以改善治疗结果.

关键词:
剂量优化工具是剂量优化工具.高剂量的甲基甲酸盐.骨质肉瘤骨质肉瘤是什么人口的药理动力学.R 闪亮的闪亮的闪亮的

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