左半球比右半球更频繁,临床过程更糟糕
Béla Clemens1, Miklós Emri2, Johanna Dömötör1
1Department of Neurology, Kenézy Gyula Campus, Faculty of Medicine, University of Debrecen, Hungary.
Epilepsy & behavior : E&B
|August 24, 2024
概括
焦点 (FE) 发作发作在左半球 (LH) 更常见,并与更糟糕的预后相关. 与右半球发作患者相比,患有左半球发作发作的患者经历的缓解较少.
科学领域:
- 神经科学是一个神经科学.
- 发病学 (Epileptology) 是一个专业的学科.
- 临床神经学 临床神经学
背景情况:
- 据报道,与左半球 (LH) 发作发作的焦点 (FE) 比右半球 (RH) 发作更频繁.
- 患有LH发作发作的患者可能会比患有RH发作的患者经历更严重的临床过程.
研究的目的:
- 在大量FE患者队列中调查发病的横向性频率.
- 为了比较LH和RH发作发作的患者之间的临床过程和治疗结果.
主要方法:
- 来自682名FE患者的临床和准临床数据的回顾性分析,其中仅LH或RH发作发作.
- 发作发作的侧面性由半观学,EEG发现和神经成像确定.
- 预后通过在药物治疗的前十年内实现五年缓解来评估.
主要成果:
- 统计学上显著的较高频率LH发作发作 (55.4%) 与RH发作发作 (44.6%) 相比,观察到 (p=0.04).
- 患有LH发作的患者显示,与患有RH发作的患者相比,五年缓解率 (33.3%) 显著较低 (41.7%) (p=0.05).
结论:
- 这项研究证实了LH发作在焦点发作的优势.
- 更糟糕的临床过程,以较低的缓解率表明,与FE患者的LH发作发生有关.
- 这些发现凸显了的横向性质,并可能影响FE的预后评估.
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