功能性发作的成年人的认知行为疗法:随机对照试验的系统审查和元分析
Pierludovico Moro1, Simona Lattanzi2, Christoph P Beier3
1Department of Human Neurosciences, Sapienza University, Rome, Italy.
Epilepsy & behavior : E&B
|August 24, 2024
概括
认知行为疗法 (CBT) 显著改善了发作自由,减少了焦虑,并提高了功能性发作 (FS) 的成年人的生活质量. 这种疗法在与标准医疗治疗相结合时是安全有效的.
科学领域:
- 神经学 神经学
- 精神病学是一个精神病学.
- 临床心理学 临床心理学
背景情况:
- 功能性 (FS) 是一种致残的疾病,通常用标准化医疗 (SMT) 治疗.
- 认知行为疗法 (CBT) 已成为FS的潜在辅助治疗方法.
- 最近的随机对照试验 (RCT) 提供了关于FS的CBT有效性和安全性的数据.
研究的目的:
- 系统地审查和分析评估FS成年人CBT的RCT.
- 评估CBT作为SMT的附加剂的有效性,与单独的SMT相比.
- 评估CBT在这个人群中的安全性.
主要方法:
- 系统性审查和RCT的元分析.
- 包括的研究比较了成年FS患者的CBT + SMT与单独的SMT.
- 主要结果:发作自由;次要结果:生活质量,焦虑和抑郁.
主要成果:
- CBT显著增加了的自由度 (OR 1.98;p=0.02).
- 认知性治疗减少了焦虑 (SMD -0.21; p=0.047) 和改善了生活质量 (SMD 0.34; p=0.003).
- 抑郁症症状没有显著差异;没有增加自杀念头或自伤的风险.
结论:
- 高质量的证据支持CBT治疗FS的有效性和安全性.
- CBT是SMT的一个有价值的补充,用于改善FS的结果.
- 未来的研究应该探索将CBT与其他疗法结合起来,以提高疗效.
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