儿童冠状腺新血管化:病因,临床特征和治疗结果
D Rego-Lorca1, J Català-Mora1, A López-de-Eguileta1
1Department of Ophthalmology, Hospital Sant Joan de Déu, Barcelona, Spain.
Archivos de la Sociedad Espanola de Oftalmologia
|August 24, 2024
概括
儿科冠状腺新血管化 (CNV) 是一种严重的疾病,通常是由贝斯特病或炎症引起的. 抗血管内皮生长因子 (VEGF) 治疗在许多儿童中显著改善了视力敏度 (VA).
科学领域:
- 眼科医生 眼科 眼科
- 儿科医学 儿科医学
- 医学研究 医学研究
背景情况:
- 儿科冠状腺新血管化 (CNV) 在诊断和管理方面提出了独特的挑战.
- 了解病因,特征和结果对于儿童有效的治疗策略至关重要.
研究的目的:
- 分析儿科胆道新血管化 (CNV) 的原因,特征,管理和结果.
- 审查有关儿科CNV的当前文献.
- 提供来自主要的三级儿科转诊医院的数据.
主要方法:
- 在2008年至2023年期间,儿童被诊断出患有CNV的病例系列.
- 收集的数据包括年龄,性别,病因,局部,抗血管内皮生长因子 (VEGF) 治疗,以及诊断时的视力敏度 (VA) 和一年的随访.
主要成果:
- 分析了31名患者的42只眼睛.
- 贝斯特病 (35.5%) 和眼内炎 (25.8%) 是最常见的原因.
- 对78.6%的眼睛进行了抗VEGF治疗,导致视力敏度显著改善 (logMAR 0.57至0.31).
结论:
- 儿科CNV是一种严重的疾病,具有显著的视觉后果.
- 在许多儿科病例中,抗VEGF治疗可以带来显著的视觉改善.
- 眼相干断层扫描 (OCT) 发现,视力障碍和 CNV 位置是治疗决策的关键因素.
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