光动力涂层杀死患者附近表面的细菌在重症监护室,低光强度的重症监护室
B Kieninger1, R Fechter1, W Bäumler2
1Department of Infection Prevention and Infectious Diseases, University Hospital Regensburg, Regensburg, Germany.
The Journal of hospital infection
|August 24, 2024
概括
抗微生物涂层 (AMC) 显著降低了医院表面的微生物数量. 标准和新型光动力学AMC都在降低重症监护室中病原体传播风险方面被证明是有效的.
科学领域:
- 感染控制的方法是感染控制.
- 材料科学是一种材料科学.
- 微生物学 微生物学
背景情况:
- 医院表面是病原体的储存库,有助于医疗保健相关的感染.
- 常规清洁只能暂时减少病原体,不可避免的再污染.
- 抗微生物涂层 (AMC) 提供了一种减轻病原体传播风险的策略.
研究的目的:
- 评估标准和新型光动力学AMCs在减少微生物负担方面的有效性.
- 在现实世界医院环境下,在低光条件下评估AMC性能.
- 为了比较两个不同的光动力学AMC与对照者的有效性.
主要方法:
- 在两个重症监护病房 (ICU) 进行了三个月的实地研究.
- 在三种类型的涂层上量化了微生物负担:标准光动力学AMC (A),新型光动力学AMC (B) 和非活性对照 (C).
- 使用eSwab收集了699个表面样本,并对每平方厘米 (cfu/cm2) 的殖民地形成单位进行了分析.
主要成果:
- 对照表面 (C) 的平均微生物负荷为5.5 ± 14.8 cfu/cm2.
- 光动力学AMC显示微生物负担明显较低:1.6 ± 4.6 cfu/cm2 (A) 和2.7 ± 9.6 cfu/cm2 (B) (P < 0.001).
- 微生物计数超过2.5 cfu/cm2的相对风险在涂层A下降了52%,在涂层B下降了40%.
结论:
- 这两种光动力学AMC均可显著而持久地减少患者附近表面的微生物数量.
- 这些发现突显了光动力学AMC在ICU感染控制方面的潜力,即使在低光照明下也是如此.
- 抗微生物涂层提供了一个有希望的方法,通过减少病原体传播来提高患者的安全性.
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