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在治疗甲状腺眼病的teprotumumab治疗后,proptosis的百分比减少

Tatiana R Rosenblatt¹, Carolina A Chiou², Michael K Yoon²

¹Department of Ophthalmology, Massachusetts Eye and Ear, Boston, Massachusetts, USA trosenblatt@meei.harvard.edu.

The British journal of ophthalmology

|August 24, 2024

概括

德鲁马布有效地降低了甲状腺眼睛疾病中的proptosis. 测量减少作为基线质的百分比提供了一个更清晰的理解teprotumumabb.

科学领域:

眼科医生眼科眼科
内分泌学在内分泌学.

背景情况:

甲状腺眼部疾病 (TED) 导致亡.
泰普穆马布是TED的治疗方法.
之前的研究以毫米的尺寸测量了亡减少.

研究的目的:

为了评估teprotumumab对proptosis的临床影响.
为了评估治疗前值的百分比,减少了proptosis.

主要方法:

对119名TED患者的回顾性分析.
测量质减少作为治疗前质的百分比.
分析了110名患者208只眼睛的数据.

主要成果:

87.4%的眼睛显示出减少了质.
平均降低治疗前亡的14.4%.
平均绝对减少为3.3毫米.

结论:

减少质的百分比更好地反映了teprotumumab的临床效果.
基于百分比的测量提高了对TED治疗影响的理解.

关键词:

科斯梅西斯的存在眼皮眼皮眼皮眼皮炎症炎症是一种炎症.轨道轨道的轨道.治疗医疗医疗

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