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Updated: Jun 15, 2025

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发现葡萄糖皮质激素的新型抗炎机制

Carolyn L Cummins1, Ido Goldstein2

  • 1Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, M5S 3M2, Canada.

Trends in endocrinology and metabolism: TEM
|August 24, 2024
PubMed
概括

葡萄糖皮质类药物通过将酸盐脱酶移动到线粒体中来增加抗炎化合物伊塔康酸. 这种伊塔科纳酸盐的产生足以减少炎症,挑战了葡萄糖皮质体受体 (GR) 对这种作用的必要性.

关键词:
这是一个很大的问题.在LPS中使用LPS.在PDH中,PDH是指PDH.这就是 itaconate.巨细胞是一个巨细胞.

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