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Updated: Jun 15, 2025

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探索在单细胞分辨率下代谢衰老的异质目标

Shuhui Sun1, Mengmeng Jiang2, Shuai Ma3

  • 1Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing 100029, China.

Trends in endocrinology and metabolism: TEM
|August 24, 2024
PubMed
概括

代谢衰老是复杂的,并且在细胞之间存在差异,影响与年龄相关的衰退. 了解细胞代谢异质性是开发健康衰老干预措施的关键.

关键词:
老化的老化 衰老的老化异质性的异质性干预干预干预干预干预干预代谢过程中的代谢.一个单细胞的单细胞.

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Mitochondria are eukaryotic cellular organelles that are known to produce energy through a process called oxidative phosphorylation. Besides their primary function, mitochondria are involved in various cellular processes, including cell growth, differentiation, signaling, metabolism, and senescence. Age-related changes cause a decline in mitochondrial quality and integrity due to increased mitochondrial mutations and oxidative damage. Thus, aging can severely impact mitochondrial functions,...
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