牛皮患者的心血管并发症:在中国的一项基于国家登记册的研究
Ping Cui1, Dengli Li2, Leyao Shi2,3
1School of Public Health, Jining Medical University, Jining, 272067, Shandong, China.
Scientific reports
|August 24, 2024
概括
中国的牛皮患者有2.62%的并发性心血管疾病 (CVD) 患病率. 危险因素包括老年,肥胖,吸烟,高血压,糖尿病和严重的牛皮.
科学领域:
- 皮肤病学和心脏病学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 牛皮是一种慢性炎症状况,已知与系统性疾病有关.
- 心血管疾病 (CVD) 是牛皮患者的重要并发症,影响预后和生活质量.
研究的目的:
- 在中国的牛皮患者中,在现实世界的临床环境中调查并发性心血管疾病 (CVD) 的患病率和流行病学特征.
- 为了确定与这种患者群体中心血管疾病存在相关的因素.
主要方法:
- 从中国国家皮肤和免疫疾病临床中心注册11560名成年牛皮患者的回顾性分析 (2020年8月至2021年9月).
- 牛皮的临床诊断遵循国家指南.
- 用单变量和多变量逻辑回归模型来确定牛皮和心血管疾病之间的关联,考虑各种人口和临床因素.
主要成果:
- 在牛皮患者中,并发性心血管疾病的总流行率为2.62% (11,560人中有236人).
- 多变量分析显示,心血管疾病与老年,肥胖,吸烟,高血压,糖尿病,药物过敏史,牛皮家族史和牛皮严重程度之间存在显著的关联.
- 在牛皮严重程度和心血管疾病风险之间观察到剂量反应关系 (Ptrend < 0.001).
结论:
- 伴随性心血管疾病在中国牛皮患者中很普遍.
- 这种人群中心血管疾病的主要风险因素包括年龄,男性性别,肥胖,吸烟,高血压,糖尿病,药物过敏史,牛皮家族史和疾病严重程度.
- 这些发现强调了查和管理牛皮患者心血管风险因素的重要性.
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