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在癌症治疗中,细菌衍生物调解药物输送:新一代战略

Muhammad Ijaz¹, Ikram Hasan², Tamoor Hamid Chaudhry³

¹School of Science, Shenzhen Key Laboratory of Flexible Printed Electronics Technology, Shenzhen Key Laboratory of Advanced Functional Carbon Materials Research and Comprehensive Application, Harbin Institute of Technology, Shenzhen, 518055, China.

Journal of nanobiotechnology

|August 24, 2024

概括

细菌衍生物通过克服传统化疗的局限性,为癌症治疗提供了一种新的方法. 本综述探讨了瘤向细菌及其衍生物,以有效地提供抗癌药物.

科学领域:

生物医学工程生物医学工程
在瘤学瘤学.
药物输送系统药物输送系统

背景情况:

癌症仍然是全球死亡的主要原因,传统化疗面临诸如瘤异质性,药物透性差,对正常细胞有毒性等挑战.
癌症的复杂性和异质性需要超越传统方法的创新治疗策略.

研究的目的:

审查瘤向细菌及其衍生物作为抗癌剂的药物输送载体的应用.
评估基于细菌的药物输送系统在癌症治疗中的优点和局限性.

主要方法:

对用于药物输送的瘤向细菌和细菌衍生物现有文献的综述.
分析表明细菌介导的抗癌药物递送的疗效和安全性的研究.

主要成果:

细菌衍生物在克服传统化疗的局限性方面表现有前途,包括改善瘤向性和减少全身毒性.
展示了各种瘤向细菌及其衍生物用于输送抗癌药物的例子.

结论:

基于细菌的药物载体在癌症治疗中具有很大的临床转化潜力.
进一步的开发可以加强它们与其他治疗方式的整合,从而导致更强大,更精确的瘤疗法.

关键词:

细菌衍生的膜囊泡来自细菌.细菌介导的癌症疗法是通过细菌介导的.细菌衍生品细菌衍生品药物交付是药物交付的过程.改造的细菌是一种工程细菌.

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