肺功能参数与急性山病有关,并且在高空和极端高度改善
Reto Reiser1, Anne-Kathrin Brill1, Christos T Nakas2
1Department of Pulmonary Medicine, Allergology and Clinical Immunology, Inselspital, Bern University Hospital, University of Bern, Switzerland.
Respiratory physiology & neurobiology
|August 25, 2024
概括
高海拔暴露改善了肺功能,峰值呼气流 (PEF) 显示与适应适应. 较低的基线PEF和FEV1与急性山病 (AMS) 风险有关,但与峰会成功无关.
科学领域:
- 生理学 生理学 生理学
- 高度医学 高度医学
背景情况:
- 高海拔环境带来生理挑战,包括降低气压和温度.
- 适应气候对于适应这些条件至关重要,可能会影响呼吸功能.
研究的目的:
- 评估高空暴露和适应对肺功能的影响.
- 为了确定肺功能是否与急性山病 (AMS) 和峰会成功有关.
主要方法:
- 在高海拔探险期间,39名受试者接受了重复的螺旋测量,高达6022米.
- 根据AMS发生情况和峰会成功情况对主题进行了分类.
主要成果:
- 肺功能参数,包括峰值呼气流 (PEF),强迫生命能力 (FVC) 和1秒内强迫呼气体积 (FEV1),随着高度的增加而增加.
- 只有PEF显示与适应改善.
- 在患有AMS的受试者中观察到较低的FEV1和海拔高度的PEF.
- 较低的基线PEF和PEF和FEV1的变化与AMS风险相关.
- 肺功能与登顶成功没有相关性.
结论:
- 肺功能通常会随着高度的增加而改善,PEF显示适应适应.
- 以前存在或发展较低的PEF和FEV1可能表明AMS的风险较高.
- 肺功能似乎不是在这些高度上成功登顶的限制因素.
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