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Updated: Jun 15, 2025

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Published on: November 29, 2024

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记忆中的活动依赖的转录程序调节中风后的运动恢复

Mary T Joy1, S Thomas Carmichael2

  • 1The Jackson Laboratory, Bar Harbor, ME, 04609, USA. maryteena.joy@jax.org.

Communications biology
|August 25, 2024
PubMed
概括

这项研究揭示了活动依赖的基因程序对记忆至关重要,通过促进神经修复来驱动中风恢复. 这些程序增强神经元功能,并指导微质相互作用用于大脑愈合.

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Long-term Potentiation

Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
Hebbian LTP
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