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Updated: May 4, 2026

Screening Bioactive Nanoparticles in Phagocytic Immune Cells for Inhibitors of Toll-like Receptor Signaling
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扩展IMQ模型:为早期药物开发提供人类TLR7反应的深度表征

Juliette A van den Noort1,2, Salma Assil1,3, Micha N Ronner1,2

  • 1Centre for Human Drug Research, Zernikedreef 8, 2333CL, Leiden, The Netherlands.

Inflammation
|August 25, 2024
PubMed
概括

局部用伊米基莫德 (IMQ) 在健康志愿者中触发了托尔类受体7 (TLR7) 介导的炎症. 长时间的IMQ暴露增强了细胞透和免疫通路活性,为免疫反应研究提供了一个模型.

关键词:
挑战 挑战 挑战 挑战艾米基基莫德 (Imiquimod) 是一种药物.长时间的暴露暴露.在TLR7中,

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