一个动态的在线名谱用于预测结肠直肠多手术后延迟的术后出血
Liting Xu1,2,3, Na Zhang1,2,3, Yongxia Zhang1,2,3
1The First Clinical Medicine, Lanzhou University, Lanzhou, 730000, Gansu, China.
Scientific reports
|August 25, 2024
概括
在结肠直肠多手术后,确定患有延迟术后出血 (DPPB) 风险的患者至关重要. 这项研究开发了一种使用风险因素,如直接口服抗凝剂和聚位置来预测DPPBD的动态名录.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 医疗信息学 医疗信息学
背景情况:
- 术后延迟出血 (DPPB) 是结肠直肠多手术后的一个重要并发症.
- 准确的风险分层对于患者管理和预防不良结果至关重要.
研究的目的:
- 为了确定内镜结直肠多角切除术后DPPBD的独立风险因素.
- 开发和验证用于预测DPPB风险的动态名ogram.
- 为临床医生提供个性化患者护理的工具.
主要方法:
- 对1544名接受内镜结肠直肠多角切除术的患者进行了回顾性分析.
- 单变量分析,LASSO和后勤回归来识别风险因素.
- 使用ROC曲线,校准图和DCA构建和验证动态名ogram.
主要成果:
- DPPB发生在38名患者 (2,46%).
- 确定了独立的危险因素:直接口服抗凝剂 (DOAC),右结肠聚体位置,更大的聚体直径,酒精消费和预防性血栓.
- 动态名图显示了高的预测准确性 (AUC 0.936培训,0.796验证,0.865全套) 和临床实用性.
结论:
- 开发的动态名图有效预测了在接受结肠直肠多手术的患者中DPPB风险.
- 诺米图表有助于早期识别高风险个体,从而实现定制的干预措施.
- 这种工具的临床应用可以提高患者的安全性和结直肠多角切除术的结果.
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